PEN-Cur is one of the most PHARMACOKINETIC curcumin supplements around...
39x Better bioavailability (1*)
50x Higher antioxidant activity (3*)
12x Greater sustained free curcumin release (1*)
9x Better absorption than piperine (Black pepper extract) added formulas (2*)
PEN-Cur's Bioavailability & Metabolism
High bioavailability and the steady release of free curcumin into the blood (12 hours) is the most important quality of PEN-Cur's unique formula, and it has been developed through innovative encapsulating technology utilising natural non-toxic biodegradable edible polymer nano-capsules.
Pre-clinical pharmacokinetics revealed that polymer encapsulated nano curcumin demonstrated at least a 9-fold increase in oral bioavailability when compared to curcumin administered with piperine as an absorption enhancer and 39 times greater bioavailability than standard curcumin that are currently being sold in the market.
PEN-Cur's nano curcumin particles are smaller than bacteria, viruses and red blood cells.
(1*) Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861163/
2*) Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. European Journal of Pharmaceutical Sciences, Volume 37, Issues 3–4, 28 June 2009, Pages 223–230 (http://www.sciencedirect.com/science/article/pii/S0928098709000621)
3*) Evolution of availability of curcumin inside poly-lactic-co-glycolic acid nanoparticles: impact on antioxidant and antinitrosant properties. PMC full text:Int J Nanomedicine. 2015; 10: 5355–5366. Published online 2015 Aug 26. doi: 10.2147/IJN.S84760 (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554401/)